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GLP-1 medications have become one of the most talked-about developments in weight management. If you've been curious about how they work — or whether they might be right for you — here's what you should know.
What are GLP-1 medications?
GLP-1 receptor agonists (like Wegovy, Zepbound, and Mounjaro) are FDA-approved prescription medications originally developed for type 2 diabetes. They work by mimicking a hormone your body already makes, helping regulate appetite and blood sugar.
They're not supplements or shortcuts. They're prescription medications prescribed by licensed clinicians after a medical evaluation.
What does treatment look like?
Most GLP-1 programs include:
- A video consultation with a licensed clinician
- Lab work to confirm you're a candidate
- A prescription for an FDA-approved, branded medication
- Ongoing check-ins and messaging with your care team
Treatment typically runs in 28-day cycles. Not everyone qualifies, and a clinician will determine whether GLP-1s are appropriate based on your health history.
How much does it cost?
This varies widely. Some programs charge $300+ per month before the cost of medication. Others have found ways to bring that down.
Sesame, for example, offers a weight loss program starting at $59 for your care and $149 for your GLP-1 medications per month. That includes video consults, labs, and unlimited messaging with your care team. They prescribe branded medications only — Wegovy, Zepbound, and Mounjaro — and work with NovoCare savings programs to help with medication costs.
What Paceline recommends
We looked at 35+ GLP-1 telehealth providers before recommending any. Sesame stood out: A+ BBB rating, 4.6/5 on Trustpilot with thousands of reviews, no legal issues, easy to cancel if it's not for you, and transparent pricing. They prescribe FDA-approved branded medications only — no compounded alternatives.
If you've been thinking about GLP-1s, Sesame is a solid place to start.
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